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Kinetic regulation of multi-ligand binding proteins
BACKGROUND: Second messengers, such as calcium, regulate the activity of multisite binding proteins in a concentration-dependent manner. For example, calcium binding has been shown to induce conformational transitions in the calcium-dependent protein calmodulin, under steady state conditions. Howeve...
Autores principales: | Salakhieva, Diana V., Sadreev, Ildar I., Chen, Michael Z. Q., Umezawa, Yoshinori, Evstifeev, Aleksandr I., Welsh, Gavin I., Kotov, Nikolay V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835871/ https://www.ncbi.nlm.nih.gov/pubmed/27090530 http://dx.doi.org/10.1186/s12918-016-0277-0 |
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