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Autophagy and modular restructuring of metabolism control germline tumor differentiation and proliferation in C. elegans
Autophagy can act either as a tumor suppressor or as a survival mechanism for established tumors. To understand how autophagy plays this dual role in cancer, in vivo models are required. By using a highly heterogeneous C. elegans germline tumor, we show that autophagy-related proteins are expressed...
Autores principales: | Gomes, Ligia C., Odedra, Devang, Dikic, Ivan, Pohl, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835962/ https://www.ncbi.nlm.nih.gov/pubmed/26759963 http://dx.doi.org/10.1080/15548627.2015.1136771 |
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