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Autophagy and modular restructuring of metabolism control germline tumor differentiation and proliferation in C. elegans

Autophagy can act either as a tumor suppressor or as a survival mechanism for established tumors. To understand how autophagy plays this dual role in cancer, in vivo models are required. By using a highly heterogeneous C. elegans germline tumor, we show that autophagy-related proteins are expressed...

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Detalles Bibliográficos
Autores principales: Gomes, Ligia C., Odedra, Devang, Dikic, Ivan, Pohl, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835962/
https://www.ncbi.nlm.nih.gov/pubmed/26759963
http://dx.doi.org/10.1080/15548627.2015.1136771

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