Vaccination with Toxoplasma gondii calcium-dependent protein kinase 6 and rhoptry protein 18 encapsulated in poly(lactide-co-glycolide) microspheres induces long-term protective immunity in mice

BACKGROUND: Toxoplasmosis is a worldwide zoonosis caused by the intracellular parasite Toxoplasma gondii. However, no effective vaccine is yet available. Poly(lactide-co-glycolide) polymers can reduce protein degradation and sustain the release of antigens over a long period, which could generate a...

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Detalles Bibliográficos
Autores principales: Zhang, Nian-Zhang, Xu, Ying, Wang, Meng, Chen, Jia, Huang, Si-Yang, Gao, Qi, Zhu, Xing-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836102/
https://www.ncbi.nlm.nih.gov/pubmed/27090890
http://dx.doi.org/10.1186/s12879-016-1496-0

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