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Vascular endothelial growth factor A as predictive marker for mTOR inhibition in relapsing high-grade serous ovarian cancer

BACKGROUND: Development of resistance against first line drug therapy including cisplatin and paclitaxel in high-grade serous ovarian cancer (HGSOC) presents a major challenge. Identifying drug candidates breaking resistance, ideally combined with predictive biomarkers allowing precision use are nee...

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Detalles Bibliográficos
Autores principales: Andorfer, Peter, Heuwieser, Alexander, Heinzel, Andreas, Lukas, Arno, Mayer, Bernd, Perco, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836190/
https://www.ncbi.nlm.nih.gov/pubmed/27090655
http://dx.doi.org/10.1186/s12918-016-0278-z