Correlation between deletion of the CDKN2 gene and tyrosine kinase inhibitor resistance in adult Philadelphia chromosome-positive acute lymphoblastic leukemia

BACKGROUND: Frequency relapses are common in Philadelphia chromosome-positive (Ph-positive) acute lymphoblastic leukemia (ALL) following tyrosine kinase inhibitors (TKIs). CDKN2A/B is believed to contribute to this chemotherapy resistance. METHODS: To further investigate the association between CDKN...

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Detalles Bibliográficos
Autores principales: Xu, Na, Li, Yu-ling, Li, Xuan, Zhou, Xuan, Cao, Rui, Li, Huan, Li, Lin, Lu, Zi-yuan, Huang, Ji-xian, Fan, Zhi-ping, Huang, Fen, Zhou, Hong-sheng, Zhang, Song, Liu, Zhi, Zhu, Hong-qian, Liu, Qi-fa, Liu, Xiao-li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836197/
https://www.ncbi.nlm.nih.gov/pubmed/27090891
http://dx.doi.org/10.1186/s13045-016-0270-5

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