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Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities
The Rho/ROCK pathway is involved in numerous pivotal cellular processes that have made it an area of intense study in cancer medicine, however, Rho-associated coiled-coil containing protein kinase (ROCK) inhibitors are yet to make an appearance in the clinical cancer setting. Their performance as an...
Autores principales: | Chin, Venessa T., Nagrial, Adnan M., Chou, Angela, Biankin, Andrew V., Gill, Anthony J., Timpson, Paul, Pajic, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836205/ https://www.ncbi.nlm.nih.gov/pubmed/26507949 http://dx.doi.org/10.1017/erm.2015.17 |
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