The emerging role of GATA transcription factors in development and disease

The GATA family of transcription factors consists of six proteins (GATA1-6) which are involved in a variety of physiological and pathological processes. GATA1/2/3 are required for differentiation of mesoderm and ectoderm-derived tissues, including the haematopoietic and central nervous system. GATA4...

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Autores principales: Lentjes, Marjolein HFM, Niessen, Hanneke EC, Akiyama, Yoshimitsu, de Bruïne, Adriaan P, Melotte, Veerle, van Engeland, Manon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836206/
https://www.ncbi.nlm.nih.gov/pubmed/26953528
http://dx.doi.org/10.1017/erm.2016.2
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author Lentjes, Marjolein HFM
Niessen, Hanneke EC
Akiyama, Yoshimitsu
de Bruïne, Adriaan P
Melotte, Veerle
van Engeland, Manon
author_facet Lentjes, Marjolein HFM
Niessen, Hanneke EC
Akiyama, Yoshimitsu
de Bruïne, Adriaan P
Melotte, Veerle
van Engeland, Manon
author_sort Lentjes, Marjolein HFM
collection PubMed
description The GATA family of transcription factors consists of six proteins (GATA1-6) which are involved in a variety of physiological and pathological processes. GATA1/2/3 are required for differentiation of mesoderm and ectoderm-derived tissues, including the haematopoietic and central nervous system. GATA4/5/6 are implicated in development and differentiation of endoderm- and mesoderm-derived tissues such as induction of differentiation of embryonic stem cells, cardiovascular embryogenesis and guidance of epithelial cell differentiation in the adult.
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spelling pubmed-48362062016-05-09 The emerging role of GATA transcription factors in development and disease Lentjes, Marjolein HFM Niessen, Hanneke EC Akiyama, Yoshimitsu de Bruïne, Adriaan P Melotte, Veerle van Engeland, Manon Expert Rev Mol Med Review Article The GATA family of transcription factors consists of six proteins (GATA1-6) which are involved in a variety of physiological and pathological processes. GATA1/2/3 are required for differentiation of mesoderm and ectoderm-derived tissues, including the haematopoietic and central nervous system. GATA4/5/6 are implicated in development and differentiation of endoderm- and mesoderm-derived tissues such as induction of differentiation of embryonic stem cells, cardiovascular embryogenesis and guidance of epithelial cell differentiation in the adult. Cambridge University Press 2016-03-08 /pmc/articles/PMC4836206/ /pubmed/26953528 http://dx.doi.org/10.1017/erm.2016.2 Text en © Cambridge University Press 2016 http://creativecommons.org/licenses/by/4.0/ This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Lentjes, Marjolein HFM
Niessen, Hanneke EC
Akiyama, Yoshimitsu
de Bruïne, Adriaan P
Melotte, Veerle
van Engeland, Manon
The emerging role of GATA transcription factors in development and disease
title The emerging role of GATA transcription factors in development and disease
title_full The emerging role of GATA transcription factors in development and disease
title_fullStr The emerging role of GATA transcription factors in development and disease
title_full_unstemmed The emerging role of GATA transcription factors in development and disease
title_short The emerging role of GATA transcription factors in development and disease
title_sort emerging role of gata transcription factors in development and disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836206/
https://www.ncbi.nlm.nih.gov/pubmed/26953528
http://dx.doi.org/10.1017/erm.2016.2
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