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Neuronal ensembles sufficient for recovery sleep and the sedative actions of α(2) adrenergic agonists
Do sedatives engage natural sleep pathways? It is usually assumed that anesthetic-induced sedation and loss-of-righting-reflex (LORR) arise by influencing the same circuitry to lesser or greater extents. For the α2 adrenergic receptor agonist dexmedetomidine, we find that sedation and LORR are in fa...
Autores principales: | Zhang, Zhe, Ferretti, Valentina, Güntan, İlke, Moro, Alessandro, Steinberg, Eleonora A., Ye, Zhiwen, Zecharia, Anna Y., Yu, Xiao, Vyssotski, Alexei L., Brickley, Stephen G., Yustos, Raquel, Pillidge, Zoe E., Harding, Edward C., Wisden, William, Franks, Nicholas P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836567/ https://www.ncbi.nlm.nih.gov/pubmed/25706476 http://dx.doi.org/10.1038/nn.3957 |
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