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Ripple-triggered stimulation of the locus coeruleus during post-learning sleep disrupts ripple/spindle coupling and impairs memory consolidation

Experience-induced replay of neuronal ensembles occurs during hippocampal high-frequency oscillations, or ripples. Post-learning increase in ripple rate is predictive of memory recall, while ripple disruption impairs learning. Ripples may thus present a fundamental component of a neurophysiological...

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Detalles Bibliográficos
Autores principales: Novitskaya, Yulia, Sara, Susan J., Logothetis, Nikos K., Eschenko, Oxana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836638/
https://www.ncbi.nlm.nih.gov/pubmed/27084931
http://dx.doi.org/10.1101/lm.040923.115