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High-throughput sequencing of partially edited trypanosome mRNAs reveals barriers to editing progression and evidence for alternative editing

Uridine insertion/deletion RNA editing in kinetoplastids entails the addition and deletion of uridine residues throughout the length of mitochondrial transcripts to generate translatable mRNAs. This complex process requires the coordinated use of several multiprotein complexes as well as the sequent...

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Detalles Bibliográficos
Autores principales: Simpson, Rachel M., Bruno, Andrew E., Bard, Jonathan E., Buck, Michael J., Read, Laurie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836643/
https://www.ncbi.nlm.nih.gov/pubmed/26908922
http://dx.doi.org/10.1261/rna.055160.115

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