Cargando…
High-throughput sequencing of partially edited trypanosome mRNAs reveals barriers to editing progression and evidence for alternative editing
Uridine insertion/deletion RNA editing in kinetoplastids entails the addition and deletion of uridine residues throughout the length of mitochondrial transcripts to generate translatable mRNAs. This complex process requires the coordinated use of several multiprotein complexes as well as the sequent...
Autores principales: | Simpson, Rachel M., Bruno, Andrew E., Bard, Jonathan E., Buck, Michael J., Read, Laurie K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836643/ https://www.ncbi.nlm.nih.gov/pubmed/26908922 http://dx.doi.org/10.1261/rna.055160.115 |
Ejemplares similares
-
Intrinsic and regulated properties of minimally edited trypanosome mRNAs
por: Tylec, Brianna L, et al.
Publicado: (2019) -
Trypanosome RNA Editing Mediator Complex proteins have distinct functions in gRNA utilization
por: Simpson, Rachel M., et al.
Publicado: (2017) -
Multiple G-quartet structures in pre-edited mRNAs suggest evolutionary driving force for RNA editing in trypanosomes
por: Leeder, W.-Matthias, et al.
Publicado: (2016) -
KREH1 RNA helicase activity promotes utilization of initiator gRNAs across multiple mRNAs in trypanosome RNA editing
por: Dubey, Ashutosh P, et al.
Publicado: (2023) -
MRB7260 is essential for productive protein–RNA interactions within the RNA editing substrate binding complex during trypanosome RNA editing
por: McAdams, Natalie M., et al.
Publicado: (2018)