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Archaea box C/D enzymes methylate two distinct substrate rRNA sequences with different efficiency

RNA modifications confer complexity to the 4-nucleotide polymer; nevertheless, their exact function is mostly unknown. rRNA 2′-O-ribose methylation concentrates to ribosome functional sites and is important for ribosome biogenesis. The methyl group is transferred to rRNA by the box C/D RNPs: The rRN...

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Detalles Bibliográficos
Autores principales: Graziadei, Andrea, Masiewicz, Pawel, Lapinaite, Audrone, Carlomagno, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836650/
https://www.ncbi.nlm.nih.gov/pubmed/26925607
http://dx.doi.org/10.1261/rna.054320.115