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Archaea box C/D enzymes methylate two distinct substrate rRNA sequences with different efficiency
RNA modifications confer complexity to the 4-nucleotide polymer; nevertheless, their exact function is mostly unknown. rRNA 2′-O-ribose methylation concentrates to ribosome functional sites and is important for ribosome biogenesis. The methyl group is transferred to rRNA by the box C/D RNPs: The rRN...
Autores principales: | Graziadei, Andrea, Masiewicz, Pawel, Lapinaite, Audrone, Carlomagno, Teresa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836650/ https://www.ncbi.nlm.nih.gov/pubmed/26925607 http://dx.doi.org/10.1261/rna.054320.115 |
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