Anti-CD47 Treatment Stimulates Phagocytosis of Glioblastoma by M1 and M2 Polarized Macrophages and Promotes M1 Polarized Macrophages In Vivo

Tumor-associated macrophages (TAMs) represent an important cellular subset within the glioblastoma (WHO grade IV) microenvironment and are a potential therapeutic target. TAMs display a continuum of different polarization states between antitumorigenic M1 and protumorigenic M2 phenotypes, with a low...

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Detalles Bibliográficos
Autores principales: Zhang, Michael, Hutter, Gregor, Kahn, Suzana A., Azad, Tej D., Gholamin, Sharareh, Xu, Chelsea Y., Liu, Jie, Achrol, Achal S., Richard, Chase, Sommerkamp, Pia, Schoen, Matthew Kenneth, McCracken, Melissa N., Majeti, Ravi, Weissman, Irving, Mitra, Siddhartha S., Cheshier, Samuel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836698/
https://www.ncbi.nlm.nih.gov/pubmed/27092773
http://dx.doi.org/10.1371/journal.pone.0153550

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