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Cytochrome P450 1A2 Metabolizes 17β-Estradiol to Suppress Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) occurs more frequently in men than in women. It is commonly agreed that estrogen plays important roles in suppressing HCC development, however, the underlying mechanism remains largely unknown. Since estrogen is mainly metabolized in liver and its metabolites affect ce...

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Detalles Bibliográficos
Autores principales: Ren, Jianwai, Chen, George G., Liu, Yi, Su, Xianwei, Hu, Baoguang, Leung, Billy C. S., Wang, Y., Ho, Rocky L. K., Yang, Shengli, Lu, Gang, Lee, C. G., Lai, Paul B. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836701/
https://www.ncbi.nlm.nih.gov/pubmed/27093553
http://dx.doi.org/10.1371/journal.pone.0153863