Cargando…
Cytochrome P450 1A2 Metabolizes 17β-Estradiol to Suppress Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) occurs more frequently in men than in women. It is commonly agreed that estrogen plays important roles in suppressing HCC development, however, the underlying mechanism remains largely unknown. Since estrogen is mainly metabolized in liver and its metabolites affect ce...
Autores principales: | Ren, Jianwai, Chen, George G., Liu, Yi, Su, Xianwei, Hu, Baoguang, Leung, Billy C. S., Wang, Y., Ho, Rocky L. K., Yang, Shengli, Lu, Gang, Lee, C. G., Lai, Paul B. S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836701/ https://www.ncbi.nlm.nih.gov/pubmed/27093553 http://dx.doi.org/10.1371/journal.pone.0153863 |
Ejemplares similares
-
In vitro inhibition of porcine cytochrome P450 by 17β -estradiol and 17α-estradiol
por: Zamaratskaia, Galia, et al.
Publicado: (2011) -
Epoxidation Activities of Human Cytochromes P450c17
and P450c21
por: Yoshimoto, Francis K., et al.
Publicado: (2014) -
Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1)
por: Simonov, Alexandr N., et al.
Publicado: (2015) -
The Role of Cytochromes P450 in Infection
por: Stavropoulou, Elisavet, et al.
Publicado: (2018) -
Sorafenib increases cytochrome P450 lipid metabolites in patient with hepatocellular carcinoma
por: Leineweber, Can G., et al.
Publicado: (2023)