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A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study

INTRODUCTION: The aim of the study was to analyse genetic architecture of RA by utilizing multiparametric statistical methods such as linear discriminant analysis (LDA) and redundancy analysis (RDA). METHODS: A total of 1393 volunteers, 499 patients with RA and 894 healthy controls were included in...

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Detalles Bibliográficos
Autores principales: Vernerova, Lucia, Spoutil, Frantisek, Vlcek, Miroslav, Krskova, Katarina, Penesova, Adela, Meskova, Milada, Marko, Andrea, Raslova, Katarina, Vohnout, Branislav, Rovensky, Jozef, Killinger, Zdenko, Jochmanova, Ivana, Lazurova, Ivica, Steiner, Guenter, Smolen, Josef, Imrich, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836711/
https://www.ncbi.nlm.nih.gov/pubmed/27092776
http://dx.doi.org/10.1371/journal.pone.0153316