Cargando…

Improving the Stability of Astaxanthin by Microencapsulation in Calcium Alginate Beads

There has been considerable interest in the biological functions of astaxanthin and its potential applications in the nutraceutical, cosmetics, food, and feed industries in recent years. However, the unstable structure of astaxanthin considerably limits its application. Therefore, this study reports...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Shen-Fu, Chen, Ying-Chen, Chen, Ray-Neng, Chen, Ling-Chun, Ho, Hsiu-O, Tsung, Yu-Han, Sheu, Ming-Thau, Liu, Der-Zen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836734/
https://www.ncbi.nlm.nih.gov/pubmed/27093175
http://dx.doi.org/10.1371/journal.pone.0153685
_version_ 1782427773943414784
author Lin, Shen-Fu
Chen, Ying-Chen
Chen, Ray-Neng
Chen, Ling-Chun
Ho, Hsiu-O
Tsung, Yu-Han
Sheu, Ming-Thau
Liu, Der-Zen
author_facet Lin, Shen-Fu
Chen, Ying-Chen
Chen, Ray-Neng
Chen, Ling-Chun
Ho, Hsiu-O
Tsung, Yu-Han
Sheu, Ming-Thau
Liu, Der-Zen
author_sort Lin, Shen-Fu
collection PubMed
description There has been considerable interest in the biological functions of astaxanthin and its potential applications in the nutraceutical, cosmetics, food, and feed industries in recent years. However, the unstable structure of astaxanthin considerably limits its application. Therefore, this study reports the encapsulation of astaxanthin in calcium alginate beads using the extrusion method to improve its stability. This study also evaluates the stability of the encapsulated astaxanthin under different storage conditions. The evaluation of astaxanthin stability under various environmental factors reveals that temperature is the most influential environmental factor in astaxanthin degradation. Stability analysis shows that, regardless of the formulation used, the content of astaxanthin encapsulated in alginate beads remains above 90% of the original amount after 21 days of storage at 25°C. These results suggest that the proposed technique is a promising way to enhance the stability of other sensitive compounds.
format Online
Article
Text
id pubmed-4836734
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-48367342016-04-29 Improving the Stability of Astaxanthin by Microencapsulation in Calcium Alginate Beads Lin, Shen-Fu Chen, Ying-Chen Chen, Ray-Neng Chen, Ling-Chun Ho, Hsiu-O Tsung, Yu-Han Sheu, Ming-Thau Liu, Der-Zen PLoS One Research Article There has been considerable interest in the biological functions of astaxanthin and its potential applications in the nutraceutical, cosmetics, food, and feed industries in recent years. However, the unstable structure of astaxanthin considerably limits its application. Therefore, this study reports the encapsulation of astaxanthin in calcium alginate beads using the extrusion method to improve its stability. This study also evaluates the stability of the encapsulated astaxanthin under different storage conditions. The evaluation of astaxanthin stability under various environmental factors reveals that temperature is the most influential environmental factor in astaxanthin degradation. Stability analysis shows that, regardless of the formulation used, the content of astaxanthin encapsulated in alginate beads remains above 90% of the original amount after 21 days of storage at 25°C. These results suggest that the proposed technique is a promising way to enhance the stability of other sensitive compounds. Public Library of Science 2016-04-19 /pmc/articles/PMC4836734/ /pubmed/27093175 http://dx.doi.org/10.1371/journal.pone.0153685 Text en © 2016 Lin et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Lin, Shen-Fu
Chen, Ying-Chen
Chen, Ray-Neng
Chen, Ling-Chun
Ho, Hsiu-O
Tsung, Yu-Han
Sheu, Ming-Thau
Liu, Der-Zen
Improving the Stability of Astaxanthin by Microencapsulation in Calcium Alginate Beads
title Improving the Stability of Astaxanthin by Microencapsulation in Calcium Alginate Beads
title_full Improving the Stability of Astaxanthin by Microencapsulation in Calcium Alginate Beads
title_fullStr Improving the Stability of Astaxanthin by Microencapsulation in Calcium Alginate Beads
title_full_unstemmed Improving the Stability of Astaxanthin by Microencapsulation in Calcium Alginate Beads
title_short Improving the Stability of Astaxanthin by Microencapsulation in Calcium Alginate Beads
title_sort improving the stability of astaxanthin by microencapsulation in calcium alginate beads
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836734/
https://www.ncbi.nlm.nih.gov/pubmed/27093175
http://dx.doi.org/10.1371/journal.pone.0153685
work_keys_str_mv AT linshenfu improvingthestabilityofastaxanthinbymicroencapsulationincalciumalginatebeads
AT chenyingchen improvingthestabilityofastaxanthinbymicroencapsulationincalciumalginatebeads
AT chenrayneng improvingthestabilityofastaxanthinbymicroencapsulationincalciumalginatebeads
AT chenlingchun improvingthestabilityofastaxanthinbymicroencapsulationincalciumalginatebeads
AT hohsiuo improvingthestabilityofastaxanthinbymicroencapsulationincalciumalginatebeads
AT tsungyuhan improvingthestabilityofastaxanthinbymicroencapsulationincalciumalginatebeads
AT sheumingthau improvingthestabilityofastaxanthinbymicroencapsulationincalciumalginatebeads
AT liuderzen improvingthestabilityofastaxanthinbymicroencapsulationincalciumalginatebeads