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Comparing Utility Scores in Common Spinal Radiculopathies: Results of a Prospective Valuation Study

Study Design Prospective observational study. Objective To determine whether preference-based health utility scores for common spinal radiculopathies vary by specific spinal level. Methods We employed a standard gamble study using the general public to calculate individual preference-based quality o...

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Autores principales: Nayak, Nikhil R., Stephen, James H., Abdullah, Kalil G., Stein, Sherman C., Malhotra, Neil R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836936/
https://www.ncbi.nlm.nih.gov/pubmed/27099818
http://dx.doi.org/10.1055/s-0035-1563406
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author Nayak, Nikhil R.
Stephen, James H.
Abdullah, Kalil G.
Stein, Sherman C.
Malhotra, Neil R.
author_facet Nayak, Nikhil R.
Stephen, James H.
Abdullah, Kalil G.
Stein, Sherman C.
Malhotra, Neil R.
author_sort Nayak, Nikhil R.
collection PubMed
description Study Design Prospective observational study. Objective To determine whether preference-based health utility scores for common spinal radiculopathies vary by specific spinal level. Methods We employed a standard gamble study using the general public to calculate individual preference-based quality of life for four common radiculopathies: C6, C7, L5, and S1. We compared utility scores obtained for each level of radiculopathy with analysis of variance and t test. Multivariable regression was used to test the effects of the covariates age, sex, and years of education. We also reviewed the literature for publications reporting EuroQol-5 Dimensions (EQ-5D) scores for patients with radiculopathy. Results Two hundred participants were included in the study. Average utility for the four spinal levels fell within a narrow range (0.748 to 0.796). There were no statistically significant differences between lumbar and cervical radiculopathies, nor were there significant differences among the different spinal levels (F = 0.0850, p = 0.086). Age and sex had no significant effect on utility scores. There was a significant correlation between years of education and utility values for S1 radiculopathy (p = 0.037). On review of the literature, no study separated utility values by specific spinal level. EQ-5D utilities for both cervical and lumbar radiculopathy were considerably lower than the results of our study. Conclusions Utility values associated with the most common levels of cervical and lumbar radiculopathy do not significantly differ from each other, validating the current practice of grouping utility by spinal segment rather than by specific root levels. The discrepancy in average utility values between our study and the EQ-5D highlights the need to be mindful of the underlying instruments used when assessing outcomes studies from different sources.
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spelling pubmed-48369362016-05-01 Comparing Utility Scores in Common Spinal Radiculopathies: Results of a Prospective Valuation Study Nayak, Nikhil R. Stephen, James H. Abdullah, Kalil G. Stein, Sherman C. Malhotra, Neil R. Global Spine J Article Study Design Prospective observational study. Objective To determine whether preference-based health utility scores for common spinal radiculopathies vary by specific spinal level. Methods We employed a standard gamble study using the general public to calculate individual preference-based quality of life for four common radiculopathies: C6, C7, L5, and S1. We compared utility scores obtained for each level of radiculopathy with analysis of variance and t test. Multivariable regression was used to test the effects of the covariates age, sex, and years of education. We also reviewed the literature for publications reporting EuroQol-5 Dimensions (EQ-5D) scores for patients with radiculopathy. Results Two hundred participants were included in the study. Average utility for the four spinal levels fell within a narrow range (0.748 to 0.796). There were no statistically significant differences between lumbar and cervical radiculopathies, nor were there significant differences among the different spinal levels (F = 0.0850, p = 0.086). Age and sex had no significant effect on utility scores. There was a significant correlation between years of education and utility values for S1 radiculopathy (p = 0.037). On review of the literature, no study separated utility values by specific spinal level. EQ-5D utilities for both cervical and lumbar radiculopathy were considerably lower than the results of our study. Conclusions Utility values associated with the most common levels of cervical and lumbar radiculopathy do not significantly differ from each other, validating the current practice of grouping utility by spinal segment rather than by specific root levels. The discrepancy in average utility values between our study and the EQ-5D highlights the need to be mindful of the underlying instruments used when assessing outcomes studies from different sources. Georg Thieme Verlag KG 2015-09-01 2016-05 /pmc/articles/PMC4836936/ /pubmed/27099818 http://dx.doi.org/10.1055/s-0035-1563406 Text en © Thieme Medical Publishers
spellingShingle Article
Nayak, Nikhil R.
Stephen, James H.
Abdullah, Kalil G.
Stein, Sherman C.
Malhotra, Neil R.
Comparing Utility Scores in Common Spinal Radiculopathies: Results of a Prospective Valuation Study
title Comparing Utility Scores in Common Spinal Radiculopathies: Results of a Prospective Valuation Study
title_full Comparing Utility Scores in Common Spinal Radiculopathies: Results of a Prospective Valuation Study
title_fullStr Comparing Utility Scores in Common Spinal Radiculopathies: Results of a Prospective Valuation Study
title_full_unstemmed Comparing Utility Scores in Common Spinal Radiculopathies: Results of a Prospective Valuation Study
title_short Comparing Utility Scores in Common Spinal Radiculopathies: Results of a Prospective Valuation Study
title_sort comparing utility scores in common spinal radiculopathies: results of a prospective valuation study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836936/
https://www.ncbi.nlm.nih.gov/pubmed/27099818
http://dx.doi.org/10.1055/s-0035-1563406
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