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Antagonism of Stem Cell Factor/c-kit Signaling Attenuates Neonatal Chronic Hypoxia-Induced Pulmonary Vascular Remodeling

BACKGROUND: Accumulating evidence suggests that c-kit positive cells are present in the remodeled pulmonary vasculature bed of patients with pulmonary hypertension (PH). Whether stem cell factor (SCF)/ c-kit regulated pathways potentiate pulmonary vascular remodeling is unknown. Here, we tested the...

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Detalles Bibliográficos
Autores principales:	Young, Karen C, Torres, Eneida, Hehre, Dorothy, Wu, Shu, Suguihara, Cleide, Hare, Joshua M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837030/ https://www.ncbi.nlm.nih.gov/pubmed/26705118 http://dx.doi.org/10.1038/pr.2015.275

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