Cargando…
A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity
14-3-3 proteins regulate biological processes by binding to phospho-Ser or phospho-Thr motifs of cellular proteins. Among them, 14-3-3ε is crucial for antiviral immunity by mediating the cytosol-to-mitochondrial-membrane translocation of the pathogen sensor RIG-I. Here we show that the NS3 protein o...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837045/ https://www.ncbi.nlm.nih.gov/pubmed/26998762 http://dx.doi.org/10.1038/ni.3393 |