Differential association of STK11 and TP53 with KRAS mutation-associated gene expression, proliferation and immune surveillance in lung adenocarcinoma

While mutations in the KRAS oncogene are amongst the most prevalent in human cancer, there are few successful treatments to target these tumors. It is also likely that heterogeneity in KRAS-mutant tumor biology significantly contributes to the response to therapy. We hypothesized that presence of co...

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Detalles Bibliográficos
Autores principales: Schabath, Matthew B., Welsh, Eric A., Fulp, William J., Chen, Lu, Teer, Jamie K., Thompson, Zachary J., Engel, Brienne E., Xie, Mengyu, Berglund, Anders E., Creelan, Ben C., Antonia, Scott J., Gray, Jhanelle E., Eschrich, Steven, Chen, Dung-Tsa, Cress, W. Douglas, Haura, Eric B., Beg, Amer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837098/
https://www.ncbi.nlm.nih.gov/pubmed/26477306
http://dx.doi.org/10.1038/onc.2015.375

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