Site-specific quantification of lysine acetylation in the N-terminal tail of histone H4 using a double-labelling, targeted UHPLC MS/MS approach

We developed a targeted liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the site-specific quantification of lysine acetylation in the N-terminal region of histone H4 by combining chemical derivatization at the protein and peptide levels with digestion using chymotrypsin and tryp...

Descripción completa

Detalles Bibliográficos
Autores principales: D’Urzo, Annalisa, Boichenko, Alexander P., van den Bosch, Thea, Hermans, Jos, Dekker, Frank, Andrisano, Vincenza, Bischoff, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837199/
https://www.ncbi.nlm.nih.gov/pubmed/26968571
http://dx.doi.org/10.1007/s00216-016-9431-1

Ejemplares similares

Ejemplares similares