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Artificial Muscle Devices: Innovations and Prospects for Fecal Incontinence Treatment

Fecal incontinence describes the involuntary loss of bowel content, which is responsible for stigmatization and social exclusion. It affects about 45% of retirement home residents and overall more than 12% of the adult population. Severe fecal incontinence can be treated by the implantation of an ar...

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Autores principales: Fattorini, Elisa, Brusa, Tobia, Gingert, Christian, Hieber, Simone E., Leung, Vanessa, Osmani, Bekim, Dominietto, Marco D., Büchler, Philippe, Hetzer, Franc, Müller, Bert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837210/
https://www.ncbi.nlm.nih.gov/pubmed/26926695
http://dx.doi.org/10.1007/s10439-016-1572-z
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author Fattorini, Elisa
Brusa, Tobia
Gingert, Christian
Hieber, Simone E.
Leung, Vanessa
Osmani, Bekim
Dominietto, Marco D.
Büchler, Philippe
Hetzer, Franc
Müller, Bert
author_facet Fattorini, Elisa
Brusa, Tobia
Gingert, Christian
Hieber, Simone E.
Leung, Vanessa
Osmani, Bekim
Dominietto, Marco D.
Büchler, Philippe
Hetzer, Franc
Müller, Bert
author_sort Fattorini, Elisa
collection PubMed
description Fecal incontinence describes the involuntary loss of bowel content, which is responsible for stigmatization and social exclusion. It affects about 45% of retirement home residents and overall more than 12% of the adult population. Severe fecal incontinence can be treated by the implantation of an artificial sphincter. Currently available implants, however, are not part of everyday surgery due to long-term re-operation rates of 95% and definitive explantation rates of 40%. Such figures suggest that the implants fail to reproduce the capabilities of the natural sphincter. This article reviews the artificial sphincters on the market and under development, presents their physical principles of operation and critically analyzes their performance. We highlight the geometrical and mechanical parameters crucial for the design of an artificial fecal sphincter and propose more advanced mechanisms of action for a biomimetic device with sensory feedback. Dielectric electro-active polymer actuators are especially attractive because of their versatility, response time, reaction forces, and energy consumption. The availability of such technology will enable fast pressure adaption comparable to the natural feedback mechanism, so that tissue atrophy and erosion can be avoided while maintaining continence during daily activities.
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spelling pubmed-48372102016-05-04 Artificial Muscle Devices: Innovations and Prospects for Fecal Incontinence Treatment Fattorini, Elisa Brusa, Tobia Gingert, Christian Hieber, Simone E. Leung, Vanessa Osmani, Bekim Dominietto, Marco D. Büchler, Philippe Hetzer, Franc Müller, Bert Ann Biomed Eng Article Fecal incontinence describes the involuntary loss of bowel content, which is responsible for stigmatization and social exclusion. It affects about 45% of retirement home residents and overall more than 12% of the adult population. Severe fecal incontinence can be treated by the implantation of an artificial sphincter. Currently available implants, however, are not part of everyday surgery due to long-term re-operation rates of 95% and definitive explantation rates of 40%. Such figures suggest that the implants fail to reproduce the capabilities of the natural sphincter. This article reviews the artificial sphincters on the market and under development, presents their physical principles of operation and critically analyzes their performance. We highlight the geometrical and mechanical parameters crucial for the design of an artificial fecal sphincter and propose more advanced mechanisms of action for a biomimetic device with sensory feedback. Dielectric electro-active polymer actuators are especially attractive because of their versatility, response time, reaction forces, and energy consumption. The availability of such technology will enable fast pressure adaption comparable to the natural feedback mechanism, so that tissue atrophy and erosion can be avoided while maintaining continence during daily activities. Springer US 2016-02-29 2016 /pmc/articles/PMC4837210/ /pubmed/26926695 http://dx.doi.org/10.1007/s10439-016-1572-z Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Article
Fattorini, Elisa
Brusa, Tobia
Gingert, Christian
Hieber, Simone E.
Leung, Vanessa
Osmani, Bekim
Dominietto, Marco D.
Büchler, Philippe
Hetzer, Franc
Müller, Bert
Artificial Muscle Devices: Innovations and Prospects for Fecal Incontinence Treatment
title Artificial Muscle Devices: Innovations and Prospects for Fecal Incontinence Treatment
title_full Artificial Muscle Devices: Innovations and Prospects for Fecal Incontinence Treatment
title_fullStr Artificial Muscle Devices: Innovations and Prospects for Fecal Incontinence Treatment
title_full_unstemmed Artificial Muscle Devices: Innovations and Prospects for Fecal Incontinence Treatment
title_short Artificial Muscle Devices: Innovations and Prospects for Fecal Incontinence Treatment
title_sort artificial muscle devices: innovations and prospects for fecal incontinence treatment
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837210/
https://www.ncbi.nlm.nih.gov/pubmed/26926695
http://dx.doi.org/10.1007/s10439-016-1572-z
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