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Genetic loci on chromosome 5 are associated with circulating levels of interleukin-5 and eosinophil count in a European population with high risk for cardiovascular disease

IL-5 is a Th2 cytokine which activates eosinophils and is suggested to have an atheroprotective role. Genetic variants in the IL5 locus have been associated with increased risk of CAD and ischemic stroke. In this study we aimed to identify genetic variants associated with IL-5 concentrations and app...

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Detalles Bibliográficos
Autores principales:	McLeod, Olga, Silveira, Angela, Valdes-Marquez, Elsa, Björkbacka, Harry, Almgren, Peter, Gertow, Karl, Gådin, Jesper R., Bäcklund, Alexandra, Sennblad, Bengt, Baldassarre, Damiano, Veglia, Fabrizio, Humphries, Steve E., Tremoli, Elena, de Faire, Ulf, Nilsson, Jan, Melander, Olle, Hopewell, Jemma C., Clarke, Robert, Björck, Hanna M., Hamsten, Anders, Öhrvik, John, Strawbridge, Rona J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Ltd 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837217/ https://www.ncbi.nlm.nih.gov/pubmed/26821299 http://dx.doi.org/10.1016/j.cyto.2016.01.007

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