A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male

Mediastinal germ cell tumors are extragonadal germ cell tumors (EGGCTs) commonly seen in children and young adults. They are more common in men. Clinically they are classified as teratomas, seminomas, and nonseminomatous germ cell tumors. Primary mediastinal yolk sac neoplasm is an extremely rare tu...

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Autores principales: Nakhla, Sammy G., Sundararajan, Srinath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837257/
https://www.ncbi.nlm.nih.gov/pubmed/27144043
http://dx.doi.org/10.1155/2016/8961486
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author Nakhla, Sammy G.
Sundararajan, Srinath
author_facet Nakhla, Sammy G.
Sundararajan, Srinath
author_sort Nakhla, Sammy G.
collection PubMed
description Mediastinal germ cell tumors are extragonadal germ cell tumors (EGGCTs) commonly seen in children and young adults. They are more common in men. Clinically they are classified as teratomas, seminomas, and nonseminomatous germ cell tumors. Primary mediastinal yolk sac neoplasm is an extremely rare tumor. We present here a very rare case of primary yolk sac tumor of the anterior mediastinum in a 73-year-old male. Mediastinal germ cell tumors have a worse prognosis than gonadal germ cell tumors. Chemotherapy followed by adjuvant surgery improves overall response in EGGCTs. However, comorbidities can render treatment with chemotherapy and surgery challenging in elderly patients.
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spelling pubmed-48372572016-05-03 A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male Nakhla, Sammy G. Sundararajan, Srinath Case Rep Oncol Med Case Report Mediastinal germ cell tumors are extragonadal germ cell tumors (EGGCTs) commonly seen in children and young adults. They are more common in men. Clinically they are classified as teratomas, seminomas, and nonseminomatous germ cell tumors. Primary mediastinal yolk sac neoplasm is an extremely rare tumor. We present here a very rare case of primary yolk sac tumor of the anterior mediastinum in a 73-year-old male. Mediastinal germ cell tumors have a worse prognosis than gonadal germ cell tumors. Chemotherapy followed by adjuvant surgery improves overall response in EGGCTs. However, comorbidities can render treatment with chemotherapy and surgery challenging in elderly patients. Hindawi Publishing Corporation 2016 2016-04-06 /pmc/articles/PMC4837257/ /pubmed/27144043 http://dx.doi.org/10.1155/2016/8961486 Text en Copyright © 2016 S. G. Nakhla and S. Sundararajan. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Nakhla, Sammy G.
Sundararajan, Srinath
A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male
title A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male
title_full A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male
title_fullStr A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male
title_full_unstemmed A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male
title_short A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male
title_sort rare case of primary anterior mediastinal yolk sac tumor in an elderly adult male
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837257/
https://www.ncbi.nlm.nih.gov/pubmed/27144043
http://dx.doi.org/10.1155/2016/8961486
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