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Interleukin-2/Anti-Interleukin-2 Immune Complex Attenuates Cardiac Remodeling after Myocardial Infarction through Expansion of Regulatory T Cells

CD4+CD25+Foxp3+ regulatory T cells (Treg cells) have protective effects in wound healing and adverse ventricular remodeling after myocardial infarction (MI). We hypothesize that the interleukin- (IL-) 2 complex comprising the recombinant mouse IL-2/anti-IL-2 mAb (JES6-1) attenuates cardiac remodelin...

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Detalles Bibliográficos
Autores principales:	Zeng, Zhipeng, Yu, Kunwu, Chen, Long, Li, Weihua, Xiao, Hong, Huang, Zhengrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837274/ https://www.ncbi.nlm.nih.gov/pubmed/27144181 http://dx.doi.org/10.1155/2016/8493767

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