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A Rat Model of Alzheimer’s Disease Based on Abeta(42) and Pro-oxidative Substances Exhibits Cognitive Deficit and Alterations in Glutamatergic and Cholinergic Neurotransmitter Systems

Alzheimer’s disease (AD) is one of the most serious human, medical, and socioeconomic burdens. Here we tested the hypothesis that a rat model of AD (Samaritan; Taconic Pharmaceuticals, USA) based on the application of amyloid beta(42) (Abeta(42)) and the pro-oxidative substances ferrous sulfate hept...

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Detalles Bibliográficos
Autores principales:	Petrasek, Tomas, Skurlova, Martina, Maleninska, Kristyna, Vojtechova, Iveta, Kristofikova, Zdena, Matuskova, Hana, Sirova, Jana, Vales, Karel, Ripova, Daniela, Stuchlik, Ales
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837344/ https://www.ncbi.nlm.nih.gov/pubmed/27148049 http://dx.doi.org/10.3389/fnagi.2016.00083

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