NLRP3 Localizes to the Tubular Epithelium in Human Kidney and Correlates With Outcome in IgA Nephropathy

Nod-like receptor pyrin domain-containing-3 (NLRP3) has been implicated in the pathogenesis of experimental renal injury, yet its characterization in human kidney disease remains largely unexplored. NLRP3 expression was evaluated in human kidney biopsies, primary renal tubular cells (HPTC) and corre...

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Detalles Bibliográficos
Autores principales: Chun, Justin, Chung, Hyunjae, Wang, Xiangyu, Barry, Rebecca, Taheri, Zohreh Mohammad, Platnich, Jaye M., Ahmed, Sofia B., Trpkov, Kiril, Hemmelgarn, Brenda, Benediktsson, Hallgrimur, James, Matthew T., Muruve, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837396/
https://www.ncbi.nlm.nih.gov/pubmed/27093923
http://dx.doi.org/10.1038/srep24667

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