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Microbial metabolite butyrate facilitates M2 macrophage polarization and function

Metabolites from intestinal microbes modulate the mucosal immune system by regulating the polarization and expansion of T cells. Whether the microbial metabolites influence macrophage polarization, however, is poorly understood. Here, we show that the large bowel microbial fermentation product, buty...

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Detalles Bibliográficos
Autores principales: Ji, Jian, Shu, Dingming, Zheng, Mingzhu, Wang, Jie, Luo, Chenglong, Wang, Yan, Guo, Fuyou, Zou, Xian, Lv, Xiaohui, Li, Ying, Liu, Tianfei, Qu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837405/
https://www.ncbi.nlm.nih.gov/pubmed/27094081
http://dx.doi.org/10.1038/srep24838