Cargando…

A recommended early goal-directed management guideline for the prevention of hypothermia-related transfusion, morbidity, and mortality in severely injured trauma patients

Hypothermia is present in up to two-thirds of patients with severe injury, although it is often disregarded during the initial resuscitation. Studies have revealed that hypothermia is associated with mortality in a large percentage of trauma cases when the patient’s temperature is below 32 °C. Risk...

Descripción completa

Detalles Bibliográficos
Autores principales: Perlman, Ryan, Callum, Jeannie, Laflamme, Claude, Tien, Homer, Nascimento, Barto, Beckett, Andrew, Alam, Asim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837515/
https://www.ncbi.nlm.nih.gov/pubmed/27095272
http://dx.doi.org/10.1186/s13054-016-1271-z
_version_ 1782427862367731712
author Perlman, Ryan
Callum, Jeannie
Laflamme, Claude
Tien, Homer
Nascimento, Barto
Beckett, Andrew
Alam, Asim
author_facet Perlman, Ryan
Callum, Jeannie
Laflamme, Claude
Tien, Homer
Nascimento, Barto
Beckett, Andrew
Alam, Asim
author_sort Perlman, Ryan
collection PubMed
description Hypothermia is present in up to two-thirds of patients with severe injury, although it is often disregarded during the initial resuscitation. Studies have revealed that hypothermia is associated with mortality in a large percentage of trauma cases when the patient’s temperature is below 32 °C. Risk factors include the severity of injury, wet clothing, low transport unit temperature, use of anesthesia, and prolonged surgery. Fortunately, associated coagulation disorders have been shown to completely resolve with aggressive warming. Selected passive and active warming techniques can be applied in damage control resuscitation. While treatment guidelines exist for acidosis and bleeding, there is no evidence-based approach to managing hypothermia in trauma patients. We synthesized a goal-directed algorithm for warming the severely injured patient that can be directly incorporated into current Advanced Trauma Life Support guidelines. This involves the early use of warming blankets and removal of wet clothing in the prehospital phase followed by aggressive rewarming on arrival at the hospital if the patient’s injuries require damage control therapy. Future research in hypothermia management should concentrate on applying this treatment algorithm and should evaluate its influence on patient outcomes. This treatment strategy may help to reduce blood loss and improve morbidity and mortality in this population of patients.
format Online
Article
Text
id pubmed-4837515
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-48375152016-04-21 A recommended early goal-directed management guideline for the prevention of hypothermia-related transfusion, morbidity, and mortality in severely injured trauma patients Perlman, Ryan Callum, Jeannie Laflamme, Claude Tien, Homer Nascimento, Barto Beckett, Andrew Alam, Asim Crit Care Review Hypothermia is present in up to two-thirds of patients with severe injury, although it is often disregarded during the initial resuscitation. Studies have revealed that hypothermia is associated with mortality in a large percentage of trauma cases when the patient’s temperature is below 32 °C. Risk factors include the severity of injury, wet clothing, low transport unit temperature, use of anesthesia, and prolonged surgery. Fortunately, associated coagulation disorders have been shown to completely resolve with aggressive warming. Selected passive and active warming techniques can be applied in damage control resuscitation. While treatment guidelines exist for acidosis and bleeding, there is no evidence-based approach to managing hypothermia in trauma patients. We synthesized a goal-directed algorithm for warming the severely injured patient that can be directly incorporated into current Advanced Trauma Life Support guidelines. This involves the early use of warming blankets and removal of wet clothing in the prehospital phase followed by aggressive rewarming on arrival at the hospital if the patient’s injuries require damage control therapy. Future research in hypothermia management should concentrate on applying this treatment algorithm and should evaluate its influence on patient outcomes. This treatment strategy may help to reduce blood loss and improve morbidity and mortality in this population of patients. BioMed Central 2016-04-20 2016 /pmc/articles/PMC4837515/ /pubmed/27095272 http://dx.doi.org/10.1186/s13054-016-1271-z Text en © Perlman et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Perlman, Ryan
Callum, Jeannie
Laflamme, Claude
Tien, Homer
Nascimento, Barto
Beckett, Andrew
Alam, Asim
A recommended early goal-directed management guideline for the prevention of hypothermia-related transfusion, morbidity, and mortality in severely injured trauma patients
title A recommended early goal-directed management guideline for the prevention of hypothermia-related transfusion, morbidity, and mortality in severely injured trauma patients
title_full A recommended early goal-directed management guideline for the prevention of hypothermia-related transfusion, morbidity, and mortality in severely injured trauma patients
title_fullStr A recommended early goal-directed management guideline for the prevention of hypothermia-related transfusion, morbidity, and mortality in severely injured trauma patients
title_full_unstemmed A recommended early goal-directed management guideline for the prevention of hypothermia-related transfusion, morbidity, and mortality in severely injured trauma patients
title_short A recommended early goal-directed management guideline for the prevention of hypothermia-related transfusion, morbidity, and mortality in severely injured trauma patients
title_sort recommended early goal-directed management guideline for the prevention of hypothermia-related transfusion, morbidity, and mortality in severely injured trauma patients
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837515/
https://www.ncbi.nlm.nih.gov/pubmed/27095272
http://dx.doi.org/10.1186/s13054-016-1271-z
work_keys_str_mv AT perlmanryan arecommendedearlygoaldirectedmanagementguidelineforthepreventionofhypothermiarelatedtransfusionmorbidityandmortalityinseverelyinjuredtraumapatients
AT callumjeannie arecommendedearlygoaldirectedmanagementguidelineforthepreventionofhypothermiarelatedtransfusionmorbidityandmortalityinseverelyinjuredtraumapatients
AT laflammeclaude arecommendedearlygoaldirectedmanagementguidelineforthepreventionofhypothermiarelatedtransfusionmorbidityandmortalityinseverelyinjuredtraumapatients
AT tienhomer arecommendedearlygoaldirectedmanagementguidelineforthepreventionofhypothermiarelatedtransfusionmorbidityandmortalityinseverelyinjuredtraumapatients
AT nascimentobarto arecommendedearlygoaldirectedmanagementguidelineforthepreventionofhypothermiarelatedtransfusionmorbidityandmortalityinseverelyinjuredtraumapatients
AT beckettandrew arecommendedearlygoaldirectedmanagementguidelineforthepreventionofhypothermiarelatedtransfusionmorbidityandmortalityinseverelyinjuredtraumapatients
AT alamasim arecommendedearlygoaldirectedmanagementguidelineforthepreventionofhypothermiarelatedtransfusionmorbidityandmortalityinseverelyinjuredtraumapatients
AT perlmanryan recommendedearlygoaldirectedmanagementguidelineforthepreventionofhypothermiarelatedtransfusionmorbidityandmortalityinseverelyinjuredtraumapatients
AT callumjeannie recommendedearlygoaldirectedmanagementguidelineforthepreventionofhypothermiarelatedtransfusionmorbidityandmortalityinseverelyinjuredtraumapatients
AT laflammeclaude recommendedearlygoaldirectedmanagementguidelineforthepreventionofhypothermiarelatedtransfusionmorbidityandmortalityinseverelyinjuredtraumapatients
AT tienhomer recommendedearlygoaldirectedmanagementguidelineforthepreventionofhypothermiarelatedtransfusionmorbidityandmortalityinseverelyinjuredtraumapatients
AT nascimentobarto recommendedearlygoaldirectedmanagementguidelineforthepreventionofhypothermiarelatedtransfusionmorbidityandmortalityinseverelyinjuredtraumapatients
AT beckettandrew recommendedearlygoaldirectedmanagementguidelineforthepreventionofhypothermiarelatedtransfusionmorbidityandmortalityinseverelyinjuredtraumapatients
AT alamasim recommendedearlygoaldirectedmanagementguidelineforthepreventionofhypothermiarelatedtransfusionmorbidityandmortalityinseverelyinjuredtraumapatients