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Farnesyl pyrophosphate synthase inhibitor, ibandronate, improves endothelial function in spontaneously hypertensive rats

Reactive oxygen species (ROS), originating predominantly from vascular smooth muscle cells (VSMCs), lead to vascular damage and endothelial dysfunction in rats with hypertension. The downstream signaling pathways of farnesyl pyrophosphate (FPP) synthase, Ras-related C3 botulinum toxin substrate 1 (R...

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Detalles Bibliográficos
Autores principales:	HAN, JIE, JIANG, DONG-MEI, YE, YANG, DU, CHANG-QING, YANG, JIAN, HU, SHEN-JIANG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838142/ https://www.ncbi.nlm.nih.gov/pubmed/27035426 http://dx.doi.org/10.3892/mmr.2016.5025

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