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Ketamine Metabolites Enantioselectively Decrease Intracellular D-Serine Concentrations in PC-12 Cells

D-Serine is an endogenous NMDA receptor co-agonist that activates synaptic NMDA receptors modulating neuronal networks in the cerebral cortex and plays a key role in long-term potentiation of synaptic transmission. D-serine is associated with NMDA receptor neurotoxicity and neurodegeneration and ele...

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Detalles Bibliográficos
Autores principales:	Singh, Nagendra S., Rutkowska, Ewelina, Plazinska, Anita, Khadeer, Mohammed, Moaddel, Ruin, Jozwiak, Krzysztof, Bernier, Michel, Wainer, Irving W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838237/ https://www.ncbi.nlm.nih.gov/pubmed/27096720 http://dx.doi.org/10.1371/journal.pone.0149499

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