Cargando…
The Role of the Insular Cortex in Retaliation
The insular cortex has consistently been associated with various aspects of emotion regulation and social interaction, including anger processing and overt aggression. Aggression research distinguishes proactive or instrumental aggression from retaliation, i.e. aggression in response to provocation....
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838249/ https://www.ncbi.nlm.nih.gov/pubmed/27096431 http://dx.doi.org/10.1371/journal.pone.0152000 |
_version_ | 1782427959186948096 |
---|---|
author | Emmerling, Franziska Schuhmann, Teresa Lobbestael, Jill Arntz, Arnoud Brugman, Suzanne Sack, Alexander Thomas |
author_facet | Emmerling, Franziska Schuhmann, Teresa Lobbestael, Jill Arntz, Arnoud Brugman, Suzanne Sack, Alexander Thomas |
author_sort | Emmerling, Franziska |
collection | PubMed |
description | The insular cortex has consistently been associated with various aspects of emotion regulation and social interaction, including anger processing and overt aggression. Aggression research distinguishes proactive or instrumental aggression from retaliation, i.e. aggression in response to provocation. Here, we investigated the specific role of the insular cortex during retaliation, employing a controlled behavioral aggression paradigm implementing different levels of provocation. Fifteen healthy male volunteers underwent whole brain functional magnetic resonance imaging (fMRI) to identify brain regions involved in interaction with either a provoking or a non-provoking opponent. FMRI group analyses were complemented by examining the parametric modulations of brain activity related to the individual level of displayed aggression. These analyses identified a hemispheric lateralization as well as an anatomical segregation of insular cortex with specifically the left posterior part being involved in retaliation. The left-lateralization of insular activity during retaliation is in accordance with evidence from electro-physiological studies, suggesting left-lateralized fronto-cortical dominance during anger processing and aggressive acts. The posterior localization of insular activity, on the other hand, suggests a spatial segregation within insular cortex with particularly the posterior part being involved in the processing of emotions that trigger intense bodily sensations and immediate action tendencies. |
format | Online Article Text |
id | pubmed-4838249 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-48382492016-04-29 The Role of the Insular Cortex in Retaliation Emmerling, Franziska Schuhmann, Teresa Lobbestael, Jill Arntz, Arnoud Brugman, Suzanne Sack, Alexander Thomas PLoS One Research Article The insular cortex has consistently been associated with various aspects of emotion regulation and social interaction, including anger processing and overt aggression. Aggression research distinguishes proactive or instrumental aggression from retaliation, i.e. aggression in response to provocation. Here, we investigated the specific role of the insular cortex during retaliation, employing a controlled behavioral aggression paradigm implementing different levels of provocation. Fifteen healthy male volunteers underwent whole brain functional magnetic resonance imaging (fMRI) to identify brain regions involved in interaction with either a provoking or a non-provoking opponent. FMRI group analyses were complemented by examining the parametric modulations of brain activity related to the individual level of displayed aggression. These analyses identified a hemispheric lateralization as well as an anatomical segregation of insular cortex with specifically the left posterior part being involved in retaliation. The left-lateralization of insular activity during retaliation is in accordance with evidence from electro-physiological studies, suggesting left-lateralized fronto-cortical dominance during anger processing and aggressive acts. The posterior localization of insular activity, on the other hand, suggests a spatial segregation within insular cortex with particularly the posterior part being involved in the processing of emotions that trigger intense bodily sensations and immediate action tendencies. Public Library of Science 2016-04-20 /pmc/articles/PMC4838249/ /pubmed/27096431 http://dx.doi.org/10.1371/journal.pone.0152000 Text en © 2016 Emmerling et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Emmerling, Franziska Schuhmann, Teresa Lobbestael, Jill Arntz, Arnoud Brugman, Suzanne Sack, Alexander Thomas The Role of the Insular Cortex in Retaliation |
title | The Role of the Insular Cortex in Retaliation |
title_full | The Role of the Insular Cortex in Retaliation |
title_fullStr | The Role of the Insular Cortex in Retaliation |
title_full_unstemmed | The Role of the Insular Cortex in Retaliation |
title_short | The Role of the Insular Cortex in Retaliation |
title_sort | role of the insular cortex in retaliation |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838249/ https://www.ncbi.nlm.nih.gov/pubmed/27096431 http://dx.doi.org/10.1371/journal.pone.0152000 |
work_keys_str_mv | AT emmerlingfranziska theroleoftheinsularcortexinretaliation AT schuhmannteresa theroleoftheinsularcortexinretaliation AT lobbestaeljill theroleoftheinsularcortexinretaliation AT arntzarnoud theroleoftheinsularcortexinretaliation AT brugmansuzanne theroleoftheinsularcortexinretaliation AT sackalexanderthomas theroleoftheinsularcortexinretaliation AT emmerlingfranziska roleoftheinsularcortexinretaliation AT schuhmannteresa roleoftheinsularcortexinretaliation AT lobbestaeljill roleoftheinsularcortexinretaliation AT arntzarnoud roleoftheinsularcortexinretaliation AT brugmansuzanne roleoftheinsularcortexinretaliation AT sackalexanderthomas roleoftheinsularcortexinretaliation |