SCARB2 variants and glucocerebrosidase activity in Parkinson’s disease

Mutations in glucocerebrosidase (GBA) are a common risk factor for Parkinson's disease (PD). The scavenger receptor class B member 2 (SCARB2) gene encodes a receptor responsible for the transport of glucocerebrosidase (GCase) to the lysosome. Two common SNPs in linkage disequilibrium with SCARB...

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Detalles Bibliográficos
Autores principales: Alcalay, Roy N, Levy, Oren A, Wolf, Pavlina, Oliva, Petra, Zhang, Xiaokui Kate, Waters, Cheryl H, Fahn, Stanley, Kang, Un Jung, Liong, Christopher, Ford, Blair, Mazzoni, Pietro, Kuo, Sheng, Johnson, Amelie, Xiong, Lan, Rouleau, Guy A, Chung, Wendy K, Marder, Karen S, Gan-Or, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838276/
https://www.ncbi.nlm.nih.gov/pubmed/27110593
http://dx.doi.org/10.1038/npjparkd.2016.4

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