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Mitochondrial dysfunction and defects in lipid homeostasis as therapeutic targets in neurodegeneration with brain iron accumulation

The PLA2G6 gene encodes a group VIA calcium independent phospholipase A2 (iPLA2β), which hydrolyses glycerophospholipids to release fatty acids and lysophospholipids. Mutations in PLA2G6 are associated with a number of neurodegenerative disorders including neurodegeneration with brain iron accumulat...

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Detalles Bibliográficos
Autores principales: Kinghorn, Kerri J., Castillo-Quan, Jorge Iván
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838319/
https://www.ncbi.nlm.nih.gov/pubmed/27141409
http://dx.doi.org/10.1080/21675511.2015.1128616

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