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Controlled DNA double-strand break induction in mice reveals post-damage transcriptome stability

DNA double-strand breaks (DSBs) and their repair can cause extensive epigenetic changes. As a result, DSBs have been proposed to promote transcriptional and, ultimately, physiological dysfunction via both cell-intrinsic and cell-non-autonomous pathways. Studying the consequences of DSBs in higher or...

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Detalles Bibliográficos
Autores principales:	Kim, Jeongkyu, Sturgill, David, Tran, Andy D., Sinclair, David A., Oberdoerffer, Philipp
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838352/ https://www.ncbi.nlm.nih.gov/pubmed/26687720 http://dx.doi.org/10.1093/nar/gkv1482

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