Cargando…

SPARC–Dependent Cardiomyopathy in Drosophila

BACKGROUND—: The Drosophila heart is an important model for studying the genetics underpinning mammalian cardiac function. The system comprises contractile cardiomyocytes, adjacent to which are pairs of highly endocytic pericardial nephrocytes that modulate cardiac function by uncharacterized mechan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hartley, Paul S., Motamedchaboki, Khatereh, Bodmer, Rolf, Ocorr, Karen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838489/ https://www.ncbi.nlm.nih.gov/pubmed/26839388 http://dx.doi.org/10.1161/CIRCGENETICS.115.001254

Ejemplares similares

A Drosophila Model of High Sugar Diet-Induced Cardiomyopathy
por: Na, Jianbo, et al.
Publicado: (2013)

Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes
por: Ivy, Jessica R., et al.
Publicado: (2015)

Genetic Variation for Cardiac Dysfunction in Drosophila
por: Ocorr, Karen A., et al.
Publicado: (2007)

The impact of SPARC on age-related cardiac dysfunction and fibrosis in Drosophila
por: Vaughan, Leigh, et al.
Publicado: (2018)

The UNC-45 Chaperone Is Critical for Establishing Myosin-Based Myofibrillar Organization and Cardiac Contractility in the Drosophila Heart Model
por: Melkani, Girish C., et al.
Publicado: (2011)

Overexpression of Kif1A in the Developing Drosophila Heart Causes Valvar and Contractility Defects: Implications for Human Congenital Heart Disease
por: Akasaka, Takeshi, et al.
Publicado: (2020)

Probing the polygenic basis of cardiomyopathies in Drosophila
por: Qian, Li, et al.
Publicado: (2012)

Drosophila as a potential model to ameliorate mutant Huntington-mediated cardiac amyloidosis
por: Trujillo, Adriana S, et al.
Publicado: (2014)

Complex Genetic Architecture of Cardiac Disease in a Wild Type Inbred Strain of Drosophila melanogaster
por: Zhang, Zhi, et al.
Publicado: (2013)

Huntington's Disease Induced Cardiac Amyloidosis Is Reversed by Modulating Protein Folding and Oxidative Stress Pathways in the Drosophila Heart
por: Melkani, Girish C., et al.
Publicado: (2013)

Multiplexin Promotes Heart but Not Aorta Morphogenesis by Polarized Enhancement of Slit/Robo Activity at the Heart Lumen
por: Harpaz, Nofar, et al.
Publicado: (2013)

ROS Regulate Cardiac Function via a Distinct Paracrine Mechanism
por: Lim, Hui-Ying, et al.
Publicado: (2014)

Statin Treatment Increases Lifespan and Improves Cardiac Health in Drosophila by Decreasing Specific Protein Prenylation
por: Spindler, Stephen R., et al.
Publicado: (2012)

SPARC: a matricellular regulator of tumorigenesis
por: Arnold, Shanna A., et al.
Publicado: (2009)

Systemic and heart autonomous effects of sphingosine Δ4 desaturase deficiency in lipotoxic cardiac pathophysiology
por: Walls, Stanley M., et al.
Publicado: (2020)

SPARC's Initiative
por: Alison Buckholtz
Publicado: (2002)

SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity
por: Rivera, Lee B., et al.
Publicado: (2011)

Identification of Redox and Glucose-Dependent Txnip Protein Interactions
por: Forred, Benjamin J., et al.
Publicado: (2016)

Evolution of dental tissue mineralization: an analysis of the jawed vertebrate SPARC and SPARC-L families
por: Enault, Sébastien, et al.
Publicado: (2018)

TGFB-INHB/activin signaling regulates age-dependent autophagy and cardiac health through inhibition of MTORC2
por: Chang, Kai, et al.
Publicado: (2019)

Prolonged Exposure to Microgravity Reduces Cardiac Contractility and Initiates Remodeling in Drosophila
por: Walls, Stanley, et al.
Publicado: (2020)

Cellular Mechanisms of Drosophila Heart Morphogenesis
por: Vogler, Georg, et al.
Publicado: (2015)

Age-dependent electrical and morphological remodeling of the Drosophila heart caused by hERG/seizure mutations
por: Ocorr, Karen, et al.
Publicado: (2017)

Extracellular matrix induced by steroids and aging through a G-protein-coupled receptor in a Drosophila model of renal fibrosis
por: Zheng, Wenjing, et al.
Publicado: (2020)

Increased SPARC expression is associated with neoadjuvant therapy in resectable pancreatic ductal adenocarcinoma
por: Hartley, Christopher, et al.
Publicado: (2020)

SPARC functions as an inhibitor of adipogenesis
por: Nie, Jing, et al.
Publicado: (2009)

Heterozygous Mutation of Drosophila Opa1 Causes the Development of Multiple Organ Abnormalities in an Age-Dependent and Organ-Specific Manner
por: Shahrestani, Parvin, et al.
Publicado: (2009)

Divergent Expression of SPARC, SPARC-L, and SCPP Genes During Jawed Vertebrate Cartilage Mineralization
por: Romero, Adrian, et al.
Publicado: (2021)

The Function of SPARC as a Mediator of Fibrosis
por: Trombetta-eSilva, Jessica, et al.
Publicado: (2012)

Drosophila as a model to study the genetic mechanisms of obesity-associated heart dysfunction
por: Diop, Soda Balla, et al.
Publicado: (2012)

Change of SPARC expression after chemotherapy in gastric cancer
por: Gao, Yong-Yin, et al.
Publicado: (2015)

The role of SPARC in extracellular matrix assembly
por: Bradshaw, Amy D.
Publicado: (2009)

Omics Overview of the SPARC Gene in Mesothelioma
por: Wu, Licun, et al.
Publicado: (2023)

Commissioning of the Laser System for SPARC Photoinjector
por: Vicario, Carlo, et al.
Publicado: (2006)

Growth hormone/IGF-I-dependent signaling restores decreased expression of the myokine SPARC in aged skeletal muscle
por: Mathes, Sebastian, et al.
Publicado: (2022)

Identification of MYOM2 as a candidate gene in hypertrophic cardiomyopathy and Tetralogy of Fallot, and its functional evaluation in the Drosophila heart
por: Auxerre-Plantié, Emilie, et al.
Publicado: (2020)

SPARC Inhibits Metabolic Plasticity in Ovarian Cancer
por: Naczki, Christine, et al.
Publicado: (2018)

Identification and characterization of a novel ISG15-ubiquitin mixed chain and its role in regulating protein homeostasis
por: Fan, Jun-Bao, et al.
Publicado: (2015)

SPARC: Structural properties associated with residue constraints
por: Neuwald, Andrew F., et al.
Publicado: (2022)

Peritumoral SPARC expression and patient outcome with resectable intrahepatic cholangiocarcinoma
por: Cheng, Chi-Tung, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_q2a7ht926b201j23jvjndlq3l0