Multicentre open-label randomised controlled trial to compare colistin alone with colistin plus meropenem for the treatment of severe infections caused by carbapenem-resistant Gram-negative infections (AIDA): a study protocol

INTRODUCTION: The emergence of antibiotic-resistant bacteria has driven renewed interest in older antibacterials, including colistin. Previous studies have shown that colistin is less effective and more toxic than modern antibiotics. In vitro synergy studies and clinical observational studies sugges...

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Detalles Bibliográficos
Autores principales: Dickstein, Yaakov, Leibovici, Leonard, Yahav, Dafna, Eliakim-Raz, Noa, Daikos, George L, Skiada, Anna, Antoniadou, Anastasia, Carmeli, Yehuda, Nutman, Amir, Levi, Inbar, Adler, Amos, Durante-Mangoni, Emanuele, Andini, Roberto, Cavezza, Giusi, Mouton, Johan W, Wijma, Rixt A, Theuretzbacher, Ursula, Friberg, Lena E, Kristoffersson, Anders N, Zusman, Oren, Koppel, Fidi, Dishon Benattar, Yael, Altunin, Sergey, Paul, Mical
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Infectious Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838684/
https://www.ncbi.nlm.nih.gov/pubmed/27098822
http://dx.doi.org/10.1136/bmjopen-2015-009956

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