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Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever

Familial Mediterranean fever (FMF) is an autoinflammatory disorder with autosomal recessive inheritance, characterized by recurrent fever and episodes of serositis. The condition is known to be caused by mutations in the MEFV (Mediterranean FeVer) gene, located in the short arm of chromosome 16. Whi...

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Autores principales: Ugan, Yunus, Doğru, Atalay, Şencan, Hüseyin, Şahin, Mehmet, Ercan Tunç, Şevket
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838801/
https://www.ncbi.nlm.nih.gov/pubmed/27143975
http://dx.doi.org/10.1155/2016/5134546
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author Ugan, Yunus
Doğru, Atalay
Şencan, Hüseyin
Şahin, Mehmet
Ercan Tunç, Şevket
author_facet Ugan, Yunus
Doğru, Atalay
Şencan, Hüseyin
Şahin, Mehmet
Ercan Tunç, Şevket
author_sort Ugan, Yunus
collection PubMed
description Familial Mediterranean fever (FMF) is an autoinflammatory disorder with autosomal recessive inheritance, characterized by recurrent fever and episodes of serositis. The condition is known to be caused by mutations in the MEFV (Mediterranean FeVer) gene, located in the short arm of chromosome 16. While more than 310 sequence variants in the MEFV gene have been described to date, the diagnosis is still established clinically. FMF may be accompanied by sacroiliitis and various forms of vasculitis. The most common forms of associated vasculitis are Henoch-Schonlein purpura and polyarteritis nodosa (PAN). We have presented here a fairly rare case of FMF, accompanied by both sacroiliitis and PAN.
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spelling pubmed-48388012016-05-03 Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever Ugan, Yunus Doğru, Atalay Şencan, Hüseyin Şahin, Mehmet Ercan Tunç, Şevket Case Rep Med Case Report Familial Mediterranean fever (FMF) is an autoinflammatory disorder with autosomal recessive inheritance, characterized by recurrent fever and episodes of serositis. The condition is known to be caused by mutations in the MEFV (Mediterranean FeVer) gene, located in the short arm of chromosome 16. While more than 310 sequence variants in the MEFV gene have been described to date, the diagnosis is still established clinically. FMF may be accompanied by sacroiliitis and various forms of vasculitis. The most common forms of associated vasculitis are Henoch-Schonlein purpura and polyarteritis nodosa (PAN). We have presented here a fairly rare case of FMF, accompanied by both sacroiliitis and PAN. Hindawi Publishing Corporation 2016 2016-04-07 /pmc/articles/PMC4838801/ /pubmed/27143975 http://dx.doi.org/10.1155/2016/5134546 Text en Copyright © 2016 Yunus Ugan et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ugan, Yunus
Doğru, Atalay
Şencan, Hüseyin
Şahin, Mehmet
Ercan Tunç, Şevket
Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever
title Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever
title_full Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever
title_fullStr Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever
title_full_unstemmed Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever
title_short Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever
title_sort sacroiliitis and polyarteritis nodosa in a patient with familial mediterranean fever
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838801/
https://www.ncbi.nlm.nih.gov/pubmed/27143975
http://dx.doi.org/10.1155/2016/5134546
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