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Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever
Familial Mediterranean fever (FMF) is an autoinflammatory disorder with autosomal recessive inheritance, characterized by recurrent fever and episodes of serositis. The condition is known to be caused by mutations in the MEFV (Mediterranean FeVer) gene, located in the short arm of chromosome 16. Whi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838801/ https://www.ncbi.nlm.nih.gov/pubmed/27143975 http://dx.doi.org/10.1155/2016/5134546 |
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author | Ugan, Yunus Doğru, Atalay Şencan, Hüseyin Şahin, Mehmet Ercan Tunç, Şevket |
author_facet | Ugan, Yunus Doğru, Atalay Şencan, Hüseyin Şahin, Mehmet Ercan Tunç, Şevket |
author_sort | Ugan, Yunus |
collection | PubMed |
description | Familial Mediterranean fever (FMF) is an autoinflammatory disorder with autosomal recessive inheritance, characterized by recurrent fever and episodes of serositis. The condition is known to be caused by mutations in the MEFV (Mediterranean FeVer) gene, located in the short arm of chromosome 16. While more than 310 sequence variants in the MEFV gene have been described to date, the diagnosis is still established clinically. FMF may be accompanied by sacroiliitis and various forms of vasculitis. The most common forms of associated vasculitis are Henoch-Schonlein purpura and polyarteritis nodosa (PAN). We have presented here a fairly rare case of FMF, accompanied by both sacroiliitis and PAN. |
format | Online Article Text |
id | pubmed-4838801 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-48388012016-05-03 Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever Ugan, Yunus Doğru, Atalay Şencan, Hüseyin Şahin, Mehmet Ercan Tunç, Şevket Case Rep Med Case Report Familial Mediterranean fever (FMF) is an autoinflammatory disorder with autosomal recessive inheritance, characterized by recurrent fever and episodes of serositis. The condition is known to be caused by mutations in the MEFV (Mediterranean FeVer) gene, located in the short arm of chromosome 16. While more than 310 sequence variants in the MEFV gene have been described to date, the diagnosis is still established clinically. FMF may be accompanied by sacroiliitis and various forms of vasculitis. The most common forms of associated vasculitis are Henoch-Schonlein purpura and polyarteritis nodosa (PAN). We have presented here a fairly rare case of FMF, accompanied by both sacroiliitis and PAN. Hindawi Publishing Corporation 2016 2016-04-07 /pmc/articles/PMC4838801/ /pubmed/27143975 http://dx.doi.org/10.1155/2016/5134546 Text en Copyright © 2016 Yunus Ugan et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Ugan, Yunus Doğru, Atalay Şencan, Hüseyin Şahin, Mehmet Ercan Tunç, Şevket Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever |
title | Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever |
title_full | Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever |
title_fullStr | Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever |
title_full_unstemmed | Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever |
title_short | Sacroiliitis and Polyarteritis Nodosa in a Patient with Familial Mediterranean Fever |
title_sort | sacroiliitis and polyarteritis nodosa in a patient with familial mediterranean fever |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838801/ https://www.ncbi.nlm.nih.gov/pubmed/27143975 http://dx.doi.org/10.1155/2016/5134546 |
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