Cargando…
Effect of Yi Gong San Decoction on Iron Homeostasis in a Mouse Model of Acute Inflammation
We investigated the effect of Yi Gong San (YGS) decoction on iron homeostasis and the possible underlying mechanisms in a mouse model of acute inflammation in this study. Our findings suggest that YGS regulates iron homeostasis by downregulating the level of HAMP mRNA, which may depend on regulation...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838806/ https://www.ncbi.nlm.nih.gov/pubmed/27143982 http://dx.doi.org/10.1155/2016/2696480 |
| _version_ | 1782428036290838528 |
|---|---|
| author | Zheng, Qin Guan, Yu Xia, Lemin Wang, Zhicheng Jiang, Yiling Zhang, Xiaofeng Wang, Jianying Wang, Guohua Pu, Yiqiong Xia, Jing Luo, Meihong |
| author_facet | Zheng, Qin Guan, Yu Xia, Lemin Wang, Zhicheng Jiang, Yiling Zhang, Xiaofeng Wang, Jianying Wang, Guohua Pu, Yiqiong Xia, Jing Luo, Meihong |
| author_sort | Zheng, Qin |
| collection | PubMed |
| description | We investigated the effect of Yi Gong San (YGS) decoction on iron homeostasis and the possible underlying mechanisms in a mouse model of acute inflammation in this study. Our findings suggest that YGS regulates iron homeostasis by downregulating the level of HAMP mRNA, which may depend on regulation of the IL-6/STAT3 or BMP/HJV/SMAD pathway during acute inflammation. |
| format | Online Article Text |
| id | pubmed-4838806 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | Hindawi Publishing Corporation |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-48388062016-05-03 Effect of Yi Gong San Decoction on Iron Homeostasis in a Mouse Model of Acute Inflammation Zheng, Qin Guan, Yu Xia, Lemin Wang, Zhicheng Jiang, Yiling Zhang, Xiaofeng Wang, Jianying Wang, Guohua Pu, Yiqiong Xia, Jing Luo, Meihong Evid Based Complement Alternat Med Research Article We investigated the effect of Yi Gong San (YGS) decoction on iron homeostasis and the possible underlying mechanisms in a mouse model of acute inflammation in this study. Our findings suggest that YGS regulates iron homeostasis by downregulating the level of HAMP mRNA, which may depend on regulation of the IL-6/STAT3 or BMP/HJV/SMAD pathway during acute inflammation. Hindawi Publishing Corporation 2016 2016-04-07 /pmc/articles/PMC4838806/ /pubmed/27143982 http://dx.doi.org/10.1155/2016/2696480 Text en Copyright © 2016 Qin Zheng et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Research Article Zheng, Qin Guan, Yu Xia, Lemin Wang, Zhicheng Jiang, Yiling Zhang, Xiaofeng Wang, Jianying Wang, Guohua Pu, Yiqiong Xia, Jing Luo, Meihong Effect of Yi Gong San Decoction on Iron Homeostasis in a Mouse Model of Acute Inflammation |
| title | Effect of Yi Gong San Decoction on Iron Homeostasis in a Mouse Model of Acute Inflammation |
| title_full | Effect of Yi Gong San Decoction on Iron Homeostasis in a Mouse Model of Acute Inflammation |
| title_fullStr | Effect of Yi Gong San Decoction on Iron Homeostasis in a Mouse Model of Acute Inflammation |
| title_full_unstemmed | Effect of Yi Gong San Decoction on Iron Homeostasis in a Mouse Model of Acute Inflammation |
| title_short | Effect of Yi Gong San Decoction on Iron Homeostasis in a Mouse Model of Acute Inflammation |
| title_sort | effect of yi gong san decoction on iron homeostasis in a mouse model of acute inflammation |
| topic | Research Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838806/ https://www.ncbi.nlm.nih.gov/pubmed/27143982 http://dx.doi.org/10.1155/2016/2696480 |
| work_keys_str_mv | AT zhengqin effectofyigongsandecoctiononironhomeostasisinamousemodelofacuteinflammation AT guanyu effectofyigongsandecoctiononironhomeostasisinamousemodelofacuteinflammation AT xialemin effectofyigongsandecoctiononironhomeostasisinamousemodelofacuteinflammation AT wangzhicheng effectofyigongsandecoctiononironhomeostasisinamousemodelofacuteinflammation AT jiangyiling effectofyigongsandecoctiononironhomeostasisinamousemodelofacuteinflammation AT zhangxiaofeng effectofyigongsandecoctiononironhomeostasisinamousemodelofacuteinflammation AT wangjianying effectofyigongsandecoctiononironhomeostasisinamousemodelofacuteinflammation AT wangguohua effectofyigongsandecoctiononironhomeostasisinamousemodelofacuteinflammation AT puyiqiong effectofyigongsandecoctiononironhomeostasisinamousemodelofacuteinflammation AT xiajing effectofyigongsandecoctiononironhomeostasisinamousemodelofacuteinflammation AT luomeihong effectofyigongsandecoctiononironhomeostasisinamousemodelofacuteinflammation |