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Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography
Lens-free digital in-line holography (LDIH) is a promising technology for portable, wide field-of-view imaging. Its resolution, however, is limited by the inherent pixel size of an imaging device. Here we present a new computational approach to achieve sub-pixel resolution for LDIH. The developed me...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838824/ https://www.ncbi.nlm.nih.gov/pubmed/27098438 http://dx.doi.org/10.1038/srep24681 |
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author | Song, Jun Leon Swisher, Christine Im, Hyungsoon Jeong, Sangmoo Pathania, Divya Iwamoto, Yoshiko Pivovarov, Misha Weissleder, Ralph Lee, Hakho |
author_facet | Song, Jun Leon Swisher, Christine Im, Hyungsoon Jeong, Sangmoo Pathania, Divya Iwamoto, Yoshiko Pivovarov, Misha Weissleder, Ralph Lee, Hakho |
author_sort | Song, Jun |
collection | PubMed |
description | Lens-free digital in-line holography (LDIH) is a promising technology for portable, wide field-of-view imaging. Its resolution, however, is limited by the inherent pixel size of an imaging device. Here we present a new computational approach to achieve sub-pixel resolution for LDIH. The developed method is a sparsity-based reconstruction with the capability to handle the non-linear nature of LDIH. We systematically characterized the algorithm through simulation and LDIH imaging studies. The method achieved the spatial resolution down to one-third of the pixel size, while requiring only single-frame imaging without any hardware modifications. This new approach can be used as a general framework to enhance the resolution in nonlinear holographic systems. |
format | Online Article Text |
id | pubmed-4838824 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-48388242016-04-27 Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography Song, Jun Leon Swisher, Christine Im, Hyungsoon Jeong, Sangmoo Pathania, Divya Iwamoto, Yoshiko Pivovarov, Misha Weissleder, Ralph Lee, Hakho Sci Rep Article Lens-free digital in-line holography (LDIH) is a promising technology for portable, wide field-of-view imaging. Its resolution, however, is limited by the inherent pixel size of an imaging device. Here we present a new computational approach to achieve sub-pixel resolution for LDIH. The developed method is a sparsity-based reconstruction with the capability to handle the non-linear nature of LDIH. We systematically characterized the algorithm through simulation and LDIH imaging studies. The method achieved the spatial resolution down to one-third of the pixel size, while requiring only single-frame imaging without any hardware modifications. This new approach can be used as a general framework to enhance the resolution in nonlinear holographic systems. Nature Publishing Group 2016-04-21 /pmc/articles/PMC4838824/ /pubmed/27098438 http://dx.doi.org/10.1038/srep24681 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Song, Jun Leon Swisher, Christine Im, Hyungsoon Jeong, Sangmoo Pathania, Divya Iwamoto, Yoshiko Pivovarov, Misha Weissleder, Ralph Lee, Hakho Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography |
title | Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography |
title_full | Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography |
title_fullStr | Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography |
title_full_unstemmed | Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography |
title_short | Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography |
title_sort | sparsity-based pixel super resolution for lens-free digital in-line holography |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838824/ https://www.ncbi.nlm.nih.gov/pubmed/27098438 http://dx.doi.org/10.1038/srep24681 |
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