Posttranslational hypusination of the eukaryotic translation initiation factor-5A regulates Fusarium graminearum virulence

Activation of eukaryotic translation initiation factor eIF5A requires a posttranslational modification, forming the unique amino acid hypusine. This activation is mediated by two enzymes, deoxyhypusine synthase, DHS, and deoxyhypusine hydroxylase, DOHH. The impact of this enzymatic complex on the li...

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Detalles Bibliográficos
Autores principales: Martinez-Rocha, Ana Lilia, Woriedh, Mayada, Chemnitz, Jan, Willingmann, Peter, Kröger, Cathrin, Hadeler, Birgit, Hauber, Joachim, Schäfer, Wilhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838825/
https://www.ncbi.nlm.nih.gov/pubmed/27098988
http://dx.doi.org/10.1038/srep24698

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