Autophagy inhibition of hsa-miR-19a-3p/19b-3p by targeting TGF-β R II during TGF-β1-induced fibrogenesis in human cardiac fibroblasts

Transforming growth factor-β1 (TGF-β1) plays an important role on fibrogenesis in heart disease. MicroRNAs have exhibited as crucial regulators of cardiac homeostasis and remodeling in various heart diseases. MiR-19a-3p/19b-3p expresses with low levels in the plasma of heart failure patients. The pu...

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Detalles Bibliográficos
Autores principales: Zou, Meijuan, Wang, Fang, Gao, Rui, Wu, Jingjing, Ou, Yingwei, Chen, Xuguan, Wang, Tongshan, Zhou, Xin, Zhu, Wei, Li, Ping, Qi, Lian-Wen, Jiang, Ting, Wang, Weiwei, Li, Chunyu, Chen, Jun, He, Qifang, Chen, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838850/
https://www.ncbi.nlm.nih.gov/pubmed/27098600
http://dx.doi.org/10.1038/srep24747

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