Multivalent display of minimal Clostridium difficile glycan epitopes mimics antigenic properties of larger glycans

Synthetic cell-surface glycans are promising vaccine candidates against Clostridium difficile. The complexity of large, highly antigenic and immunogenic glycans is a synthetic challenge. Less complex antigens providing similar immune responses are desirable for vaccine development. Based on molecula...

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Detalles Bibliográficos
Autores principales: Broecker, Felix, Hanske, Jonas, Martin, Christopher E., Baek, Ju Yuel, Wahlbrink, Annette, Wojcik, Felix, Hartmann, Laura, Rademacher, Christoph, Anish, Chakkumkal, Seeberger, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838876/
https://www.ncbi.nlm.nih.gov/pubmed/27091615
http://dx.doi.org/10.1038/ncomms11224

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