Super-complexes of adhesion GPCRs and neural guidance receptors

Latrophilin adhesion-GPCRs (Lphn1–3 or ADGRL1–3) and Unc5 cell guidance receptors (Unc5A–D) interact with FLRT proteins (FLRT1–3), thereby promoting cell adhesion and repulsion, respectively. How the three proteins interact and function simultaneously is poorly understood. We show that Unc5D interac...

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Detalles Bibliográficos
Autores principales: Jackson, Verity A., Mehmood, Shahid, Chavent, Matthieu, Roversi, Pietro, Carrasquero, Maria, del Toro, Daniel, Seyit-Bremer, Goenuel, Ranaivoson, Fanomezana M., Comoletti, Davide, Sansom, Mark S. P., Robinson, Carol V., Klein, Rüdiger, Seiradake, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838878/
https://www.ncbi.nlm.nih.gov/pubmed/27091502
http://dx.doi.org/10.1038/ncomms11184

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