NETosis and lack of DNase activity are key factors in Echis carinatus venom-induced tissue destruction

Indian Echis carinatus bite causes sustained tissue destruction at the bite site. Neutrophils, the major leukocytes in the early defence process, accumulate at the bite site. Here we show that E. carinatus venom induces neutrophil extracellular trap (NET) formation. The NETs block the blood vessels...

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Detalles Bibliográficos
Autores principales: Katkar, Gajanan D., Sundaram, Mahalingam S., NaveenKumar, Somanathapura K., Swethakumar, Basavarajaiah, Sharma, Rachana D., Paul, Manoj, Vishalakshi, Gopalapura J., Devaraja, Sannaningaiah, Girish, Kesturu S., Kemparaju, Kempaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838891/
https://www.ncbi.nlm.nih.gov/pubmed/27093631
http://dx.doi.org/10.1038/ncomms11361

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