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Imaging mass spectrometry for the precise design of antibody-drug conjugates

Antibody-drug conjugates (ADCs) are a class of immunotherapeutic agents that enable the delivery of cytotoxic drugs to target malignant cells. Because various cancers and tumour vascular endothelia strongly express anti-human tissue factor (TF), we prepared ADCs consisting of a TF-specific monoclona...

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Detalles Bibliográficos
Autores principales:	Fujiwara, Yuki, Furuta, Masaru, Manabe, Shino, Koga, Yoshikatsu, Yasunaga, Masahiro, Matsumura, Yasuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838941/ https://www.ncbi.nlm.nih.gov/pubmed/27098163 http://dx.doi.org/10.1038/srep24954

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