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ERK1/2, MEK1/2 and p38 downstream signalling molecules impaired in CD56(dim)CD16(+) and CD56(bright)CD16(dim/−) natural killer cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis patients

BACKGROUND: Natural Killer (NK) cell effector functions are dependent on phosphorylation of the mitogen-activated protein kinases (MAPK) pathway to produce an effective immune response for the clearance of target cells infected with viruses, bacteria or malignantly transformed cells. Intracellular s...

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Detalles Bibliográficos
Autores principales:	Huth, Teilah Kathryn, Staines, Donald, Marshall-Gradisnik, Sonya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839077/ https://www.ncbi.nlm.nih.gov/pubmed/27098723 http://dx.doi.org/10.1186/s12967-016-0859-z

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