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iPSC-derived mesenchymal stromal cells are less supportive than primary MSCs for co-culture of hematopoietic progenitor cells

In vitro culture of hematopoietic stem and progenitor cells (HPCs) is supported by a suitable cellular microenvironment, such as mesenchymal stromal cells (MSCs)—but MSCs are heterogeneous and poorly defined. In this study, we analyzed whether MSCs derived from induced pluripotent stem cells (iPS-MS...

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Detalles Bibliográficos
Autores principales: Vasko, Theresa, Frobel, Joana, Lubberich, Richard, Goecke, Tamme W., Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839158/
https://www.ncbi.nlm.nih.gov/pubmed/27098268
http://dx.doi.org/10.1186/s13045-016-0273-2