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In vitro and in vivo neuroprotective effects of cJun N-terminal kinase inhibitors on retinal ganglion cells

BACKGROUND: The c-Jun N-terminal kinase (JNK) signaling pathway plays an important role in neuronal pathophysiology. Using JNK inhibitors, we examined involvement of the JNK pathway in cultured rat retinal ganglion cell (RGC) death and in mouse retinal ischemia/reperfusion (I/R) injury of the visual...

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Detalles Bibliográficos
Autores principales:	Kim, Byung-Jin, Silverman, Sean M., Liu, Yang, Wordinger, Robert J., Pang, Iok-Hou, Clark, Abbot F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839164/ https://www.ncbi.nlm.nih.gov/pubmed/27098079 http://dx.doi.org/10.1186/s13024-016-0093-4

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